Restriction digests of the clone give the following sizes (kb): EcoRI--4.6; BamHI--2.8, 1.8; EcoRI/BamHI--2.8, 1.8; EcoRI/HindIII--2.8, 1.8, 0.3; AccI--uncut. Codominant segregation demonstrated in 56 3-generation families. Maps to the pericentromeric region. RFLPs observed under normal conditions of hybridization and washing. Enzyme(s) not detecting polymorphism: RsaI, TaqI. |