| Insert |
DNA: genomic Insert lengths(kb): 15.0 Tissue: liver Gene product: DNA Segment, single copy [D11S127] Alleles: A8, A1, A7, A2, A5, A6, A3, A4 |
| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--20.0, 11.0, 5.8, 4.7, 2.5, 1.8; SmaI-->23.0, 8.5, 2.3; BglII--20.0, 8.2, 5.3, 4.4, 2.2, 2.0, 1.8, 1.3; BamHI--18.0, 14.0, 6.2, 4.2, 2.1; HindIII--21.0, 10.0, 6.4, 4.7, 3.0, 2.4. Enzyme(s) not detecting polymorphism: BamHI, BglII, EcoRI, HindIII, HincII, RsaI, TaqI (panel of 5 individuals). |
| References |
Schumm JW, et al. Identification of more than 500 RFLPs by screening random genomic clones. Am. J. Hum. Genet. 42: 143-159, 1988. PubMed: 2892396
Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638
Kazazian HH Jr., et al. Characterization of a spontaneous mutation to a B-thalassemia allele. Am. J. Hum. Genet. 38: 860-867, 1986. PubMed: 3014870
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