| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--23.0, 12.0, 5.0, 4.4, 3.8, 3.4, 1.5; BamHI--23.0, 14.0, 7.4, 5.6, 4.0, 1.5, 0.96; HindIII-->23.0, 14.0, 6.0, 4.0, 3.4, 1.5, 0.76; BglII-->23.0, 8.0, 4.6, 3.4, 2.6, 1.9, 1.7, 1.2, 0.64; PvuI-->23.0, 15.0, 4.6, 2.5, 2.0. The MspI and RsaI polymorphisms have a combined PIC value of 0.71 and a combined heterozygosity of 71%. |
| References |
Schumm JW, et al. Identification of more than 500 RFLPs by screening random genomic clones. Am. J. Hum. Genet. 42: 143-159, 1988. PubMed: 2892396
Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638
Kazazian HH Jr., et al. Characterization of a spontaneous mutation to a B-thalassemia allele. Am. J. Hum. Genet. 38: 860-867, 1986. PubMed: 3014870
Knowlton RG, et al. Use of highly polymorphic DNA probes for genotypic analysis following bone marrow transplantation. Blood 68: 378-385, 1986. PubMed: 3524708
Jacobsen SJ, et al. A clinically homogeneous group of families with facioscapulohumeral (Landouzy-Dejerine) muscular dystrophy: linkage analysis of six autosomes. Am. J. Hum. Genet. 47: 376-388, 1990. PubMed: 1975474
Weiffenbach B, et al. A genetic linkage map of human chromosome 5 with 60 RFLP loci. Genomics 10: 173-185, 1991. PubMed: 1675192
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