| Insert |
DNA: genomic Insert lengths(kb): 5.099999904632568 Gene product: DNA Segment, single copy [D7S16] Alleles: A1, A1, A2, A2 |
| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--5.0, 3.0; PvuII--5.8, 2.0, 0.3; BglI--8.0; PvuI--8.0; HindIII--8.0. Linked to the cystic fibrosis locus at a recombination fraction of 0.045. Enzyme(s) not detecting polymorphism: BamHI, NciI, SacI, RsaI, TaqI, BclI, SacI, PvuII, BglII, PstI, MspI, HindIII, AvaII, XmnI, HaeIII, HincII, EcoRV, HinfI. |
| References |
Scambler PJ, et al. Isolation of a further anonymous informative DNA sequence from chromosome seven closely linked to cystic fibrosis. Nucleic Acids Res. 14: 1951-1956, 1986. PubMed: 3960715
Zengerling S, et al. Mapping of DNA markers linked to the cystic fibrosis locus on the long arm of chromosome 7. Am. J. Hum. Genet. 40: 228-236, 1987. PubMed: 3472464
Buckle VJ, et al. Localisation of a sequence, 7C22, showing close linkage to the cystic fibrosis locus. Cytogenet. Cell Genet. 44: 41-42, 1987. PubMed: 3469063
Lathrop GM, et al. Refined linkage map of chromosome 7 in the region of the cystic fibrosis gene. Am. J. Hum. Genet. 42: 38-44, 1988. PubMed: 2892400
Wainwright BJ, et al. Regional localization of three probes closely linked to the cystic fibrosis locus by deletion analysis. Cytogenet. Cell Genet. 44: 101-102, 1987. PubMed: 3471388
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