| Comments |
Restriction digests of the clone give the following sizes (kb): BamHI--23.0, 7.6, 6.4, 5.4, 4.0; EcoRI--21.0, 12.0, 7.6, 3.0, 2.1, 1.2; HindIII--23.0, 6.6, 5.6, 5.4, 2.7, 1.8; XbaI--24.0, 13.0, 5.4, 2.3; KpnI--18.0 (doublet), 5.4, 3.2, 1.4. The EcoRI and HindIII polymorphisms have a combined PIC value of 0.55 and a combined heterozygosity of 57%. Enzyme(s) not detecting polymorphism: BamHI, BglII, HincII, MspI, PstI (panel of 5 individuals). |
| References |
Schumm JW, et al. Identification of more than 500 RFLPs by screening random genomic clones. Am. J. Hum. Genet. 42: 143-159, 1988. PubMed: 2892396
Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638
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