| 產(chǎn)品名稱 |
Dengue virus type 4 |
| 商品貨號(hào) |
B177211 |
| Classification |
Flaviviridae, Flavivirus |
| Agent |
Dengue virus type 4 |
| Strain |
H241 (TC adapted) |
| Applications |
Vector borne research |
| Biosafety Level |
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Isolation |
derived from existing strain |
| Product Format |
frozen |
| Storage Conditions |
-70°C or colder |
| Comments |
This virus appears to be one cause of Southeast Asian mosquito-borne hemorrhagic fever and has also been associated with classical Dengue fever. Many additional strains have been isolated from serum of human patients and Aedes aegypti and Aedes albopictus. |
| Effect on Host |
Yes, in vitro effects: Cytopathic effects in tissue culture (focal cell degeneration and inhibited cell growth) CPE in TC (focal cell degeneration and inhibited cell growth); death of sM Yes, in vivo effects: death of suckling mice |
| Recommended Host |
Mus musculus
mouse
Homo sapiens
human
Host of Choice: RhMkK TC Host Range:? sM (i.c. or i.p.); RhMk (i.c.); MkK TC |
| Growth Conditions |
Duration: 4-10 days at 37C in tissue culture; 4-6 days in suckling mice |
| Cryopreservation |
Storage temperature: -70C or lower |
| Name of Depositor |
W Brandt, ATCC |
| Special Collection |
NCRR Contract |
| Source |
derived from existing strain |
| References |
Hammon WM, et al. Viruses associated with epidemic hemorrhagic fevers of the Philippines and Thailand. Science 131(3407): 1102-1103, 1960. PubMed: 14399343
Hammon WM, et al. New hemorrhagic fevers of children in the Philippines and Thailand. Trans Assoc Am Physicians 73:140-155, 1960. PubMed: 13711073
Derived at the ATCC from ATCC VR-217 (mouse passaged material, no longer available) by tissue culture passage in LLC-MK2 cells.
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