Tissue: renal cell carcinoma
Disease: von Hippel-Lindau tumor
Type of DNA: genomic
Insert ends: BamHI, Sau3AI
Insert size (kb): 40.0
Genbank accession: AF010238 (partial sequence)
Insert Size (kb)
40.0
Media
ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Shipping Information
Frozen glycerol stock of E. coli containing the cosmid.
Comments
Contains exon 1 of VHL disease tumor suppressor gene critical region deleted in renal cell carcinomas and approx. 30kb region upstream.
References
Latif F, et al. Identification of the von Hippel-Lindau disease Tumor Suppressor Gene. Science 260: 1317-1320, 1993. PubMed: 8493574
Kuzmin I, et al. One-megabase yeast artificial chromosome and 400-kilobase cosmid-phage contigs containing the von Hippel-Lindau tumor suppressor and Ca(2+)-transporting adenosine triphosphatase isoform 2 genes. Cancer Res. 54: 2486-2491, 1994. PubMed: 8162598
