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歷史搜索:A549    293T 金黃色葡萄球菌 大腸桿菌 AKK菌
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B0.7 [p528B0.7]
B0.7 [p528B0.7]
規格:
價格:
編號:B239471
品牌:Mingzhoubio

標準菌株
定量菌液
DNA
RNA

規格:
凍干粉
斜面
甘油
平板


產品名稱
B0.7 [p528B0.7]
商品貨號
B239471
Designations
B0.7 [p528B0.7]
Species
Homo sapiens, human
培養基
Depositors
Temple University, CM Croce, Temple University
Applications
Has been used to detect t(1;14)(p32;q11) translocations associated with certain acute T-cell leukemias based on the size of the EcoRI fragment detected.
Vector
Construct size (kb): 3.400000095367432
Insert
DNA: genomic
Insert lengths(kb): 0.699999988079071
Tissue: acute T-lymphoblastic leukemia DU.528 cell line
Gene product: T-cell acute lymphocytic leukemia 1 (NOTE: redefinition of symbol)(T cell lymphoma 5, helix-loop-helix protein tal-1, 34 kDa) [TAL*]
Insert Size (kb)
0.700
Biosafety Level
1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Comments
Restriction digests of the clone give the following sizes (kb): BamHI--2.6, .72; EcoRI--3.7; HindIII--3.7.
Derived from a germ-line fragment that includes what would be the 1p+ translocation breakpoint in the DU.528 cell line.
Detects a human genomic germline EcoRI fragment of 17.5 kb.
Has been used to detect t(1;14)(p32;q11) translocations associated with certain acute T-cell leukemias based on the size of the EcoRI fragment detected.
Detects transcripts of 5.4, 2.6, and 2.2 kb from TAL1 (TCL5).
References

Croce CM. TCL-5 gene rearrangement involved in T-cell leukemia and melanoma. US Patent 5,242,795 dated Sep 7 1993

Finger LR, et al. Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma. Proc. Natl. Acad. Sci. USA 86: 5039-5043, 1989. PubMed: 2740341

Disclosure
This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
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