| Insert |
DNA: genomic Insert lengths(kb): 3.599999904632568 Gene product: DNA Segment, single copy [D22S24] Alleles: A1, A2, B1, B2 |
| Comments |
Restriction digests of the clone give the following sizes (kb): HindIII--3.6, 2.7; PstI--3.2, 1.2, 0.6 (doublet), 0.4, 0.3; SalI--6.3; XbaI--2.9, 2.7, 0.8; BamHI--3.9, 2.4. W21G (ATCC 61628, 61629) and p22/34 (ATCC 61576, 61577) hybridize to the same pair of SacII fragments and therefore cannot be separated by more than 380 kb. The PIC value for the haplotype for the TaqI and MspI polymorphisms is 0.57. |
| References |
Rouleau GA, et al. A genetic linkage map of the long arm of human chromosome 22. Genomics 4: 1-6, 1989. PubMed: 2563348
Carey AH, et al. Localization of 27 DNA markers to the region of human chromosome 22q11-pter deleted in patients with the DiGeorge syndrome and duplicated in the der22 syndrome. Genomics 7: 299-306, 1990. PubMed: 2365351
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