特征特性
Derived from the pleural fluid of a patient with small cell lung cancer; the cells express elevated levels of the 4biochemical markers characteristic of SCLC: neuron-specific enolase, the brain isoenzyme of creatine kinase, L- 背景描述 dopa decarboxylase and bombesin-like immunoreactivity; the cells stain posittively for keratin and vimentin butare negative for neurofilament triplet protein; the cells express relatively high amounts of c-myc mRNA, but noamplification of the gene is detected.